Specific Causes of Structural Coma

Jerome B. Posner, Clifford B. Saper, Nicholas D. Schiff and Fred Plum

in Plum and Posner's Diagnosis of Stupor and Coma

Fourth edition

Published on behalf of Oxford University Press

Published in print February 2008 | ISBN: 9780195321319
Published online April 2013 | e-ISBN: 9780199322954 | DOI:

Series: Contemporary Neurology Series

Specific Causes of Structural Coma

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This chapter discusses, in turn, the specific causes of supratentorial and infratentorial compressive and destructive lesions that cause coma. Although these designations are useful for rapid bedside diagnosis, it is of course possible for a lesion such as an intracerebral hemorrhage both to destroy and to compress normal tissues. Extracerebral mass lesions can also cause sufficient compression to lead to infarction (i.e., tissue destruction). Thus, in some instances, the division is arbitrary. However, the types of conditions that cause the compression versus destruction of neural tissue tend to be distinct, and often they have distinct clinical presentations as well. The guide provided in this chapter, while not exhaustive, is meant to cover the most commonly encountered causes and ones where understanding their pathophysiology can influence diagnosis and treatment (Table 4–1).

Chapter.  33259 words.  Illustrated.

Subjects: Neurology

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