Chapter

Blood–Nervous System Barrier Dysfunction: Pathophysiology and Treatment

Lisa M. Deangelis and Jerome B. Posner

in Neurologic Complications of Cancer

Second edition

Published on behalf of Oxford University Press

Published in print September 2008 | ISBN: 9780195366747
Published online April 2013 | e-ISBN: 9780199322879 | DOI: http://dx.doi.org/10.1093/med/9780195366747.003.0003

Series: Contemporary Neurology Series

Blood–Nervous System Barrier Dysfunction: Pathophysiology and Treatment

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This chapter covers blood-nervous system barrier dysfunction, and its pathophysiology and treatment. It includes an introduction of why the anatomy and physiology of the nervous system makes it particularly vulnerable to the effects of metastases, disruption of blood-central nervous system barriers and its consequences, transport of chemotherapeutic drugs across the blood-brain barrier, and restoration of blood-central nervous system barriers.

Chapter.  17001 words.  Illustrated.

Subjects: Neurology

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