Chapter

Side Effects of Chemotherapy

Lisa M. Deangelis and Jerome B. Posner

in Neurologic Complications of Cancer

Second edition

Published on behalf of Oxford University Press

Published in print September 2008 | ISBN: 9780195366747
Published online April 2013 | e-ISBN: 9780199322879 | DOI: http://dx.doi.org/10.1093/med/9780195366747.003.0012

Series: Contemporary Neurology Series

Side Effects of Chemotherapy

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Patients with cancer often take several different types of drugs (Table 12–1). Some drugs, including antineoplastic, hormonal, or biologic agents, treat the cancer. Others treat symptoms related to the cancer or the side effects of antineoplastics. In addition, because many patients with cancer are elderly, they may also be taking drugs for comorbid illnesses such as hypertension or cardiac disease that are unrelated to the underlying cancer. Finally, a significant number of patients take unconventional agents,1 often not informing the physician that they are doing so. Some drugs from each category, acting alone or with other agents, are neurotoxic. Experimental antineoplastic agents, the side effects of which are not completely known, may also be neurotoxic. Thus, neurotoxicity caused by medication must be high on the list of potential causes of otherwise unexplained neurologic symptoms.

Chapter.  41192 words.  Illustrated.

Subjects: Neurology

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