DTI and Tractography in Neurosurgical Planning

Christopher A. Clark and Tiernan Byrnes

in Diffusion MRI

Published on behalf of Oxford University Press

Published in print November 2010 | ISBN: 9780195369779
Published online September 2012 | e-ISBN: 9780199965144 | DOI:
DTI and Tractography in Neurosurgical Planning

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This chapter explores the use of DTI and tractography for pre-surgical evaluation which can be used to assess white matter tract anatomy and involvement in the presence of a lesion. An overview of the considerations for neurosurgical planning and the use of DTI color encoded direction maps are described. Early studies using tractography for neurosurgical planning are examined providing the foundation for current approaches. The importance of validation is underlined, the principal mechanism for this being comparison with electro-cortical stimulation. A review of studies examining clinically eloquent tracts is provided including descending motor pathway, optic radiations and arcuate fasciculus. The importance of intra-operative brain shift is discussed in the context of intra-operative update of tractography. Reproducibility of reconstructed tracts is examined. The role of tractography in neurosurgical planning of vascular lesions and in functional neurosurgery is discussed followed by a summary of future directions and developments.

Chapter.  10107 words.  Illustrated.

Subjects: Neuroscientific Techniques

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