Chapter

Brain Chemistry: Magnetic Resonance Spectroscopy

Stephen R. Dager, Neva M. Corrigan, Todd L. Richards and Dennis W. Shaw

in Autism Spectrum Disorders

Published on behalf of Oxford University Press

Published in print May 2011 | ISBN: 9780195371826
Published online September 2012 | e-ISBN: 9780199965212 | DOI: http://dx.doi.org/10.1093/med/9780195371826.003.0038
Brain Chemistry: Magnetic Resonance Spectroscopy

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  • Child and Adolescent Psychiatry
  • Neurology
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Magnetic resonance spectroscopy (MRS) can provide useful insights into mechanisms that may account for brain structural alternations in autism spectrum disorders. This chapter begins with a discussion of the development and applications of MRS. It then considers advances in MRS and MRS findings in ASD. 1H MRS is advancing our understanding of basic mechanisms underlying brain developmental abnormalities associated with ASD, such as the early cerebral enlargement observed by MRI. 1H MRS findings, to date, from studies of ASD do not appear to be of diagnostic specificity but can be used to interrogate brain structural alterations in ASD and relationships to specific developmental time points.

Chapter.  13228 words.  Illustrated.

Subjects: Child and Adolescent Psychiatry ; Neurology ; Neuroscience

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