Chapter

Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders

Meera E. Modi and Larry J. Young

in Autism Spectrum Disorders

Published on behalf of Oxford University Press

Published in print May 2011 | ISBN: 9780195371826
Published online September 2012 | e-ISBN: 9780199965212 | DOI: http://dx.doi.org/10.1093/med/9780195371826.003.0039
Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders

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  • Child and Adolescent Psychiatry
  • Neurology
  • Neuroscience

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This chapter examines the role that oxytocin, arginine vasopressin, and their related systems play in mediating the core components of social behavior. It discusses their involvement in both normal social behavior and how their disregulation leads to disturbances in behavior. Parallels are drawn between the neurobiological findings in animal models and the genetic and imaging studies done in both typical and clinical human populations. Finally, the direct evidence implicating a role for these neuropeptide systems in autism spectrum disorders is presented with a discussion of how these findings may shape the development of novel pharmacological therapies for treating social impairment.

Chapter.  13084 words.  Illustrated.

Subjects: Child and Adolescent Psychiatry ; Neurology ; Neuroscience

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