Chapter

Known and Possible Roles of Epigenetics in Autism

Richard Person, Xinna Zhang, Soeun Kim, Marwan Shinawi and Arthur L. Beaudet

in Autism Spectrum Disorders

Published on behalf of Oxford University Press

Published in print May 2011 | ISBN: 9780195371826
Published online September 2012 | e-ISBN: 9780199965212 | DOI: http://dx.doi.org/10.1093/med/9780195371826.003.0048
Known and Possible Roles of Epigenetics in Autism

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This chapter reviews the known and hypothetical roles of epigenetics in the etiology of autism. It discusses the biochemistry and molecular biology of epigenetic regulation; biology and heritability of epigenetics; epimutations and transgenerational inheritance; methods for epigenetic analysis; difficulties encountered in epigenetic studies of human disease; epigenetics and disease states; epimutations that cause disease; epigenetics and autism, schizophrenia, and related phenotypes; examples of studies of postmortem brain in autism; and the potential for epigenetic therapy.

Chapter.  13749 words.  Illustrated.

Subjects: Child and Adolescent Psychiatry ; Neurology ; Neuroscience

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