Chapter

Autism and Environmental Genomics: Synergistic Systems Approaches to Autism Complexity

Mark A. Corrales and Martha R. Herbert

in Autism Spectrum Disorders

Published on behalf of Oxford University Press

Published in print May 2011 | ISBN: 9780195371826
Published online September 2012 | e-ISBN: 9780199965212 | DOI: http://dx.doi.org/10.1093/med/9780195371826.003.0056
Autism and Environmental Genomics: Synergistic Systems Approaches to Autism Complexity

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  • Child and Adolescent Psychiatry
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This chapter outlines how genetic and environmental factors may converge on common mechanisms pertinent to neurodevelopmental disorders, and the ways that high heritability can involve not only high genetic but also high environmental contributions. The chapter is organized as follows. Part One discusses the mechanisms by which genome and environment work together. Part Two considers the methodological pitfalls in assessing relative contributions of genes, environment, and gene-environment interactions in a disorder with high heritability. Part Three focuses on research directions and resources.

Chapter.  14023 words.  Illustrated.

Subjects: Child and Adolescent Psychiatry ; Neurology ; Neuroscience

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