Chapter

Zebrafish As a Tool to Study Autism

Alicia Blaker-Lee, Gianluca DeRienzo and Hazel Sive

in Autism Spectrum Disorders

Published on behalf of Oxford University Press

Published in print May 2011 | ISBN: 9780195371826
Published online September 2012 | e-ISBN: 9780199965212 | DOI: http://dx.doi.org/10.1093/med/9780195371826.003.0057
Zebrafish As a Tool to Study Autism

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  • Child and Adolescent Psychiatry
  • Neurology
  • Neuroscience

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This chapter discusses the use of the zebrafish as a tool to study the activity of genes implicated in autism and other mental health disorders. This tool will be extremely useful in meeting the challenge of assaying activity of human gene variants connected to autism. In addition, the fish provides an outstanding whole animal vertebrate system, which can be used in small molecule screens for modulation of gene function associated with autism.

Chapter.  8201 words.  Illustrated.

Subjects: Child and Adolescent Psychiatry ; Neurology ; Neuroscience

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