Somatosensory Evoked Potentials

Jonathan L. Carter and J. Clarke Stevens

in Clinical Neurophysiology

Third edition

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print April 2009 | ISBN: 9780195385113
Published online April 2013 | e-ISBN: 9780199322770 | DOI:

Series: Contemporary Neurology Series

Somatosensory Evoked Potentials

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SEPs recorded with surface electrodes represent volume-conducted activity arising from myelinated peripheral and central axons, synapses in central gray matter, and changes in the size and shape of the volume conductor. They provide an objective measure of function in large-diameter myelinated sensory afferents peripherally and in proprioceptive pathways centrally. Changes in amplitude and latency can be used to localize lesions in the nervous system, to identify objectively abnormalities in patients with few sensory manifestations or none at all, and to monitor function over time.

Chapter.  12365 words.  Illustrated.

Subjects: Neurology

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