Assessing The Neuromuscular Junction With Repetitive Stimulation Studies

Andrea J. Boon

in Clinical Neurophysiology

Third edition

Published on behalf of © Mayo Foundation for Medical Education and Research

Published in print April 2009 | ISBN: 9780195385113
Published online April 2013 | e-ISBN: 9780199322770 | DOI:

Series: Contemporary Neurology Series

Assessing The Neuromuscular Junction With Repetitive Stimulation Studies

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The electrophysiologic technique of repetitive stimulation is an important component of the evaluation of patients with fatigue, weakness, ptosis, diplopia, dysphagia, or dysarthria. The technique requires a knowledge of the physiology and pathophysiology of neuromuscular transmission and the basic techniques of nerve conduction studies for proper application and interpretation. Errors in technique can produce falsely positive or negative results. The test must be individualized for each case, with the proper selection of nerve and muscle combinations, rates of stimulation, and types of exercise. The examiner must be aware of the varied abnormalities that occur with different disease entities.

Chapter.  7926 words.  Illustrated.

Subjects: Neurology

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