Microcircuits of the Striatum

J. Paul Bolam

in Handbook of Brain Microcircuits

Published on behalf of Oxford University Press

Published in print August 2010 | ISBN: 9780195389883
Published online September 2012 | e-ISBN: 9780199965137 | DOI:
Microcircuits of the Striatum

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The striatum, or caudate-putamen (or caudate nucleus and putamen in those species in which they are divided by the internal capsule) is the major division of the basal ganglia, a group of structures involved in a variety of processes, including movement and cognitive and mnemonic functions. The striatum consists of a population of principal neurons, the medium-sized densely spiny neurons (MSNs), which are the projection neurons of the striatum, several populations of GABAergic interneurons, and a population of cholinergic interneurons. This chapter discusses MSNs and their excitatory afferents, sculpting of the response of MSNs by GABA transmission, and modulatory control of the activity of MSNs.

Chapter.  4087 words.  Illustrated.

Subjects: Development of the Nervous System

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