Hippocampus: Network Physiology

György Buzsáki

in Handbook of Brain Microcircuits

Published on behalf of Oxford University Press

Published in print August 2010 | ISBN: 9780195389883
Published online September 2012 | e-ISBN: 9780199965137 | DOI:
Hippocampus: Network Physiology

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Information in the entorhinal-hippocampal system is transferred through alternating layers of recurrent excitatory and largely parallel-organized networks, allowing for the iterative integration and segregation of messages. The local computations require time and the speed of layer-to-layer transfer of information is largely determined by the dynamics of network oscillations. The temporal integration within coherent theta oscillations sets constraints on the resolution of both spatial and non-spatial information and the number of items brought up from long-term memory. Theta and other oscillatory dynamics can generate self-organized assembly sequences that reflect a compressed version of experienced firing sequence patterns during exploration. The entorhinal input can modify the initiators of hippocampal assembly sequences, while the remaining assembly members are recruited mainly by local mechanisms.

Chapter.  4039 words.  Illustrated.

Subjects: Development of the Nervous System

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