Chapter

Spinal Cord: Dorsal Horn

Tiphaine Dolique, Marc Landry and Frédéric Nagy

in Handbook of Brain Microcircuits

Published on behalf of Oxford University Press

Published in print August 2010 | ISBN: 9780195389883
Published online September 2012 | e-ISBN: 9780199965137 | DOI: http://dx.doi.org/10.1093/med/9780195389883.003.0023
Spinal Cord: Dorsal Horn

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This chapter discusses the global structure and cyto-architectonic organization of the doral horm (DH), morphological characteristics of DH neurons, neural circuitry, and plasticity of DH microcircuits. The DH of the spinal cord is the first central site where incoming somatosensory signals are processed, and it is an essential stage of synaptic integration in the pain pathway. Neuronal circuitry in the DH comprises four principal elements: firstly, central axonal terminals of primary afferent sensory neurons; secondly, intrinsic spinal cord interneurons (INs); thirdly, projection neurons (PNs) ascending to the brain; and finally, terminals of axons descending from the brain.

Chapter.  4874 words.  Illustrated.

Subjects: Development of the Nervous System

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