Chapter

Mechanisms of Ischemic/Hypoxic Brain Injury

Gary A. Rosenberg

in Molecular Physiology and Metabolism of the Nervous System

Published on behalf of Oxford University Press

Published in print April 2012 | ISBN: 9780195394276
Published online April 2013 | e-ISBN: 9780199322831 | DOI: http://dx.doi.org/10.1093/med/9780195394276.003.0007

Series: Contemporary Neurology Series

Mechanisms of Ischemic/Hypoxic Brain Injury

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This chapter covers the mechanisms of ischemic/hypoxic brain injury, including epidemiology, risk factors, and prevention of stroke; molecular cascade in ischemic tissue results from energy failure; excitatory and inhibitory neurotransmitters; neuroinflammation in stroke; proteases in hypoxia/ischemia; caspases and cell death; tissue inhibitors of metalloproteinases and apoptosis; tight junction proteins and MMPS; MMPS and TPA-induced bleeding, animal models in stroke; arteriovenous malformations and cavernous hemangiomas; MRI, PET, and EPR in hypoxia/ischemia.

Chapter.  12386 words.  Illustrated.

Subjects: Neurology

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