Chapter

HIV-1 Immunology

Sabita Roy, Krishnakumar Devadas, Subhash Dhawan and Shilpa Buch

in The Neurology of AIDS

Third edition

Published on behalf of Oxford University Press

Published in print December 2011 | ISBN: 9780195399349
Published online September 2012 | e-ISBN: 9780199965199 | DOI: http://dx.doi.org/10.1093/med/9780195399349.003.0002
HIV-1 Immunology

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  • Disorders of the Nervous System
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This chapter serves as a bridge between the molecular and structural biology of the human immunodeficiency virus type one (HIV-1) and the immunological consequences that viral infection produces. The innate and adaptive immune system and their responses play a critical role in the control of HIV replication. Unfortunately, immune dysfunction is common in HIV-infected individuals and the virus as well is capable of developing strategies to evade host defenses. Thus, in most untreated individuals, if viral replication is not fully contained, persistent viremia is sustained eventually resulting in progressive disease and the development of acquired immunodeficiency syndrome (AIDS).

Chapter.  13621 words.  Illustrated.

Subjects: Disorders of the Nervous System ; Infectious Diseases

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