Murine Models for NeuroAIDS

Larisa Y. Poluektova

in The Neurology of AIDS

Third edition

Published on behalf of Oxford University Press

Published in print December 2011 | ISBN: 9780195399349
Published online September 2012 | e-ISBN: 9780199965199 | DOI:
Murine Models for NeuroAIDS

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  • Disorders of the Nervous System
  • Infectious Diseases


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Among the animal models for HIV disease, non-human primates infected with SIV or chimeric SIV/HIV viruses best mimic human disease. However, limitations in cost and availability have limited the extent of research with these animals. For this and other reasons, mouse models, particularly those using immunodeficient and transgenic mice, have played an essential role. This chapter reviews these two important types of murine models.

Chapter.  14303 words.  Illustrated.

Subjects: Disorders of the Nervous System ; Infectious Diseases

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