Pathobiology of HIV-related Neuropathies

Nicholas W. S. Davies and Bruce J. Brew

in The Neurology of AIDS

Third edition

Published on behalf of Oxford University Press

Published in print December 2011 | ISBN: 9780195399349
Published online September 2012 | e-ISBN: 9780199965199 | DOI:
Pathobiology of HIV-related Neuropathies

More Like This

Show all results sharing these subjects:

  • Disorders of the Nervous System
  • Infectious Diseases


Show Summary Details


HIV-associated neuropathies remain the cause of considerable morbidity. The pathobiology of these neuropathies is complex, resulting from many mechanisms through which HIV interacts with the immune and nervous systems. Additional complexity arises because antiretroviral medications can themselves cause or contribute to neuropathy, both directly and through the metabolic complications of long-term treatment. This chapter presents a general conceptual framework for understanding the neuropathies and then discusses specific neuropathies. The concepts discussed are time locking, layering, and non-specific pathology. The specific neuropathies discussed are distal symmetrical sensory polyneuropathy, antiretroviral toxic neuropathies, inflammatory demyelinating neuropathies, mononeuritic multiplex, diffuse infiltrative lymphocytosis syndrome, cytomegalovirus polyradiculopathy, syphilitic polyradiculopathy, human T-lymphotropic virus neuropathy, and statin neuropathy.

Chapter.  7914 words.  Illustrated.

Subjects: Disorders of the Nervous System ; Infectious Diseases

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.