Chapter

Infants, Children, and Adolescents

Annelies Van Rie and Anna Dow

in The Neurology of AIDS

Third edition

Published on behalf of Oxford University Press

Published in print December 2011 | ISBN: 9780195399349
Published online September 2012 | e-ISBN: 9780199965199 | DOI: http://dx.doi.org/10.1093/med/9780195399349.003.0064
Infants, Children, and Adolescents

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  • Disorders of the Nervous System
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In children, HIV infection is associated with a wide range of neurodevelopmental delays and neuropsychiatric complications, as well as an increased risk of central nervous system (CNS) infections, neoplasms, and cerebrovascular complications. Highly active antiretroviral therapy (HAART) has resulted in a dramatic decrease in severe presentations of HIV infection (such as HIV encephalopathy), but milder forms of neurodevelopmental delay and behavioral problems are likely to continue occurring in HIV-infected children, even those who are clinically and immunologically stable. This chapter summarizes current knowledge about CNS disease manifestations in HIV-positive children infected by mother-to-child transmission. The chapter discusses both developed and developing countries and emphasizes knowledge relevant to the era of antiretroviral treatment.

Chapter.  16096 words. 

Subjects: Disorders of the Nervous System ; Infectious Diseases

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