Antiretroviral Nanotherapies

Madhavan P. N. Nair and Zainulabedin M. Saiyed

in The Neurology of AIDS

Third edition

Published on behalf of Oxford University Press

Published in print December 2011 | ISBN: 9780195399349
Published online September 2012 | e-ISBN: 9780199965199 | DOI:
Antiretroviral Nanotherapies

More Like This

Show all results sharing these subjects:

  • Disorders of the Nervous System
  • Infectious Diseases


Show Summary Details


Although highly active anti-retroviral therapy has significantly reduced the severity of HIV disease, complete eradication of virus from hard-to-access reservoirs in the HIV-infected patient remains a major challenge. The central nervous system, protected by its blood-brain barrier (BBB), represents one of the major anatomical reservoirs for HIV-1. Nanotechnology-based drug delivery systems have shown tremendous potential for penetrating the BBB and targeting antiretroviral drugs to the brain. This review highlights selected nanotechnology-based drug delivery systems that hold the potential for future effective treatment of HIV-associated neurocognitive disorders. Results from our laboratory on the use of magnetically-guided nanocarrier-based drug delivery systems for targeting active forms of antiretroviral drugs to the brain are discussed.

Chapter.  4439 words.  Illustrated.

Subjects: Disorders of the Nervous System ; Infectious Diseases

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.