Everyday Impact of HIV-Associated Neurocognitive Disorders

Thomas D. Marcotte, J. Cobb Scott, Charles H. Hinkin and Robert K. Heaton

in The Neurology of AIDS

Third edition

Published on behalf of Oxford University Press

Published in print December 2011 | ISBN: 9780195399349
Published online September 2012 | e-ISBN: 9780199965199 | DOI:
Everyday Impact of HIV-Associated Neurocognitive Disorders

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  • Disorders of the Nervous System
  • Infectious Diseases


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Rates of HIV-associated neurocognitive disorders (HAND) are not markedly different now from what they were during the pre-HAART era, though the most severe form of HAND, dementia, is less common now than previously and, overall, there has been a shift within the HAND spectrum towards mild-to-moderate impairments. There is now substantial evidence that HIV-associated neurocognitive impairments less severe than dementia can significantly affect daily functioning. In this chapter, we detail research regarding the effects of HAND on survival, quality of life, instrumental activities of daily living, medication adherence, vocational functioning, automobile driving, and other specific cognitive aspects of everyday functioning. We conclude with recommendations for future research.

Chapter.  13862 words. 

Subjects: Disorders of the Nervous System ; Infectious Diseases

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