Sites of MS attack and clinically isolated syndromes

John Zajicek, Jennifer Freeman and Bernadette Porter

in Multiple Sclerosis Care - A Practical Manual

Published on behalf of Oxford University Press

Published in print July 2007 | ISBN: 9780198569831
Published online November 2012 | e-ISBN: 9780191753138 | DOI:

Series: Oxford Care Manuals

Sites of MS attack and clinically isolated syndromes

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Typical presentations of clinically isolated syndromes - Differential diagnosis in MS and clinically isolated syndromes - Specific demyelinating syndromes -

MS tends to present with specific syndromes, with a predilection to attack particular parts of the central nervous system, namely the optic nerves, the spinal cord and the brainstem. This is partly because these co-called eloquent areas contain a high density of important nerve pathways so that relatively small areas of inflammation may have significant clinical effects, which are readily noticed. However, they may also be other reasons to do with blood supply and expression of particular molecules that may play a role in the pathogenesis of MS.

Chapter.  4374 words.  Illustrated.

Subjects: Neurology

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