Chapter

Fatty liver disease in children

R. Mark Beattie, Anil Dhawan and John W.L. Puntis

in Paediatric Gastroenterology, Hepatology and Nutrition

Published on behalf of Oxford University Press

Published in print March 2009 | ISBN: 9780198569862
Published online October 2011 | e-ISBN: 9780191725968 | DOI: https://dx.doi.org/10.1093/med/9780198569862.003.0055

Series: Oxford Specialist Handbooks

Fatty liver disease in children

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Demographics 406

Pathophysiology 406

Differential diagnoses 407

Presenting features 407

Investigation 408

Management 409

Fatty liver disease is now increasingly recognized in children, particularly in the setting of obesity.

The term non-alcoholic steatohepatitis (NASH) was first coined in 1980 by Ludwig to describe a pattern of liver injury in adults in which the liver histology was consistent with alcoholic hepatitis, but in whom significant alcohol consumption was denied. NASH can be considered as part of a broader spectrum of non-alcoholic fatty liver disease that extends from simple steatosis through steatohepatitis that is characterized by the potential to progress to fibrosis, cirrhosis and subsequent end stage liver disease....

Chapter.  922 words. 

Subjects: Gastroenterology ; Paediatrics

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