Chapter

Cancer immunity and clinical oncology

Maries van den Broek, Lotta von Boehmer, Kunle Odunsi and Alexander Knuth

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2010 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.0604

Series: Oxford Textbooks

Cancer immunity and clinical oncology

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Patients develop immune-mediated defence mechanisms against cancers, which are referred to as the ‘three E’s’: (1) elimination—corresponding to immunological control of the tumour or immunosurveillance; (2) equilibrium—the process by which the immune response iteratively selects/promotes less immunogenic tumour variants; and (3) escape—when the immunologically sculptured tumour expands in an uncontrolled manner....

Chapter.  7054 words.  Illustrated.

Subjects: Medical Oncology

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