Chapter

Physiological changes, clinical features, and general management of infected patients

Todd W. Rice and Gordon R. Bernard

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.070102_update_001

Series: Oxford Textbooks

Physiological changes, clinical features, and general management of infected patients

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The host response to an infectious stimulus involves an intricate link between the inflammatory and coagulation systems, also mechanisms designed to limit damage to normal tissues. Key elements are: (1) the inflammatory cascade—antigens from infectious agents stimulate macrophages and monocytes (and other cells) via Toll-like receptors to release tumour necrosis factor ...

Chapter.  6113 words.  Illustrated.

Subjects: Medical Microbiology and Virology ; Infectious Diseases

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