Chapter

Antimicrobial chemotherapy

R.G. Finch

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.070205_update_001

Series: Oxford Textbooks

Antimicrobial chemotherapy

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The practice of medicine changed dramatically with the availability of effective antimicrobial agents. Fatal diseases such as bacterial meningitis and endocarditis became treatable; much minor community infectious morbidity became readily controlled; many surgical procedures became much safer, and developments in solid organ and bone marrow transplantation became possible. However, the very success of antimicrobial chemotherapy has led to overuse, misuse and inappropriate pressures from the public to prescribe. In many countries, antibiotics are freely available to the public for purchase ‘over the counter’, with few controls or guidance to ensure their safe and effective use. The emergence and spread of antimicrobial resistance worldwide and the decline in development and licensing of new antimicrobials threaten the future successful treatment of bacterial infections....

Chapter.  13360 words.  Illustrated.

Subjects: Clinical Medicine ; Infectious Diseases

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