Chapter

Herpesviruses (excluding Epstein–Barr virus)

J.G.P. Sissons

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.070502_update_001

Series: Oxford Textbooks

Herpesviruses (excluding Epstein–Barr virus)

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Eight human herpesviruses, all with a linear double-stranded DNA genome and divided into alpha-, beta-, and gamma-subfamilies on the basis of genomic and biological properties, share the capacity to produce latent infection. The diseases they cause may result from primary infection, or reactivation of the virus from latency, and tend to be more severe in immunosuppressed patients. Diagnosis of the various herpesvirus infections may be made on clinical grounds alone, by culture or demonstration of viral particles by electron microscopy of relevant samples, by serological testing, or (increasingly) by PCR-based tests....

Chapter.  16525 words.  Illustrated.

Subjects: Medical Microbiology and Virology ; Infectious Diseases

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