Chapter

Epstein–Barr virus

M.A. Epstein and A.B. Rickinson

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.070503_update_002

Series: Oxford Textbooks

Epstein–Barr virus

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Epstein–Barr virus (EBV) is a human herpesvirus with a linear double-stranded DNA genome that is carried asymptomatically by most people. Symptomless primary infection is usual in childhood, establishing a lifelong carrier state where the virus persists as a latent infection of circulating B cells. The virus replicates recurrently in oropharyngeal epithelial cells, with consequent shedding of virus in saliva transmitting infection....

Chapter.  5580 words.  Illustrated.

Subjects: Medical Microbiology and Virology ; Infectious Diseases

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