Marina S. Morgan

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI:

Series: Oxford Textbooks


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  • Medical Microbiology and Virology
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Pasteurella multocida is an important human Gram-negative pathogen residing primarily in the oropharynx of mammals and transmitted through bites and scratches. Presentation is typically within 12 h of the injury with rapidly spreading cellulitis or sepsis, leading to serious morbidity and mortality (up to 40%) if untreated. Diagnosis is clinical: fresh bite wound cultures are unhelpful, but the organism may be cultured in cases with established infection. Treatment requires thorough wound debridement, with delayed closure if possible, along with antimicrobials to provide empirical cover against pasteurellae and other expected pathogens, e.g. amoxicillin-clavulanate plus ciprofloxacin, or imipenem plus ...

Chapter.  1794 words.  Illustrated.

Subjects: Medical Microbiology and Virology ; Infectious Diseases

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