Chapter

<i>Francisella tularensis</i> infection

Petra C.F. Oyston

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.070619_update_001

Series: Oxford Textbooks

Francisella tularensis infection

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Fransicella tularensis is a small Gram-negative coccobacillus that circulates in small rodents, rabbits and hares, most frequently in Scandinavia, northern North America, Japan, and Russia. Clinical presentation depends on the route of infection. Most commonly this follows the bite of an infected arthropod vector, resulting in ulceroglandular tularaemia. The most acute and life-threatening disease, respiratory or pneumonic tularaemia, arises following inhalation of infectious aerosols or dusts. The organism is highly fastidious, requiring rich media for isolation and specialized reagents for positive identification; most cases are diagnosed serologically. Treatment is with supportive care and antibiotics (usually ciprofloxacin, doxycycline or gentamicin). There is no vaccine....

Chapter.  2285 words.  Illustrated.

Subjects: Medical Microbiology and Virology ; Infectious Diseases

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