Chapter

<i>Penicillium marneffei</i> infection

Thira Sirisanthana

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.070706_update_001

Series: Oxford Textbooks

Penicillium marneffei infection

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Penicillium marneffei infection is very rare in the immunocompetent but one of the most common opportunistic infections in HIV-infected people in South-East Asia, north-eastern India, southern China, Hong Kong, and Taiwan. Presentation is usually with fever, chills, lymphadenopathy, hepatomegaly, and splenomegaly, with skin lesions—most commonly papules with central necrotic umbilication—in two-thirds of cases. Diagnosis is made by microscopy of bone marrow aspirate or biopsy specimens. Standard treatment, which is usually effective, is with amphotericin B followed by itraconazole....

Chapter.  1370 words.  Illustrated.

Subjects: Medical Microbiology and Virology ; Infectious Diseases

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