<i>Cyclospora</i> and cyclosporiasis

R. Lainson

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI:

Series: Oxford Textbooks

Cyclospora and cyclosporiasis

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  • Medical Microbiology and Virology
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Most species of Cyclospora (Protozoa: Apicomplexa: Eimeriidae) are parasites of various reptiles and mammals. C. cayetanensis, which probably infects only humans, is transmitted by way of resistant oocysts voided in the faeces and contaminating food or water. Distribution is worldwide, particularly in regions with a low level of hygiene. Clinical presentation is with explosive outbreaks of acute diarrhoea, with this infection now regarded as an important causative agent of traveller’s diarrhoea. Diagnosis is dependent on detection of oocysts in faeces by direct examination or in stained faecal smears. Aside from supportive care, treatment with trimethoprim–sulfamethoxazole has proved effective in eliminating the parasite in immunocompetent patients, but relapses are common in those with AIDS. Prevention is by ensuring good general hygiene, and in areas of high endemicity water should be boiled before drinking or use in preparation of fruits/vegetables that are to be eaten raw....

Chapter.  1952 words.  Illustrated.

Subjects: Medical Microbiology and Virology ; Infectious Diseases

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