Liver fluke infections

David I. Grove

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2012 | e-ISBN: 9780199570973 | DOI:

Series: Oxford Textbooks

Liver fluke infections

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  • Medical Microbiology and Virology
  • Infectious Diseases


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Clonorchis (syn. Opisthorchis) sinensis is a fluke (flatworm) acquired by ingestion of undercooked freshwater fish in eastern Asia. Larvae in the duodenum enter the biliary tree through the sphincter of Oddi and mature. Most patients are asymptomatic, but there may be right upper abdominal discomfort, and infection can be complicated by bacterial cholangitis and there is an increased risk of cholangiocarcinoma. Diagnosis is suggested by finding eggs in faeces or in duodenal aspirates, but can only be confirmed by examination of adult flukes. Treatment is with praziquantel....

Chapter.  3319 words.  Illustrated.

Subjects: Medical Microbiology and Virology ; Infectious Diseases

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