Chapter

Ulcerative colitis

D.P. Jewell

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online November 2011 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.1512_update_001

Series: Oxford Textbooks

Ulcerative colitis

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Case History—A 23 yr old woman presenting with a short history of bloody diarrhoea.

Ulcerative colitis is a chronic inflammatory disease of the colon that always affects the rectum, extends proximally to a variable extent, and is characterized by a relapsing and remitting course. In mild disease the mucosa is hyperaemic and granular; punctate ulcers appear in more severe disease, and these may then enlarge and extend deeply. Infiltration with acute and chronic inflammatory cells is largely confined to the mucosa, with histological features of chronicity, e.g. distorted crypt architecture, important in clinical distinction from other causes of colitis, e.g. infective....

Chapter.  11517 words.  Illustrated.

Subjects: Gastroenterology

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