Sjögren’s syndrome

Patrick J.W. Venables and Elizabeth Price

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online November 2011 | e-ISBN: 9780199570973 | DOI:

Series: Oxford Textbooks

Sjögren’s syndrome

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Sjögren’s syndrome is an autoimmune connective tissue disease characterized by dryness of the eyes and mouth and lymphocytic infiltrates in the salivary, lachrymal, and other exocrine glands. Its cause is not known, but the condition may be primary, where the disease exists on its own, or secondary, where it is associated with other rheumatic diseases, most commonly rheumatoid arthritis. It affects women more than men (ratio 9:1) and is the second commonest autoimmune rheumatic disease (after rheumatoid arthritis), but in many patients remains undiagnosed because symptoms are usually mild....

Chapter.  3573 words.  Illustrated.

Subjects: Rheumatology

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