Chapter

Osteomyelitis

Anthony R. Berendt and Martin McNally

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2010 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.2003

Series: Oxford Textbooks

Osteomyelitis

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Bacteria can obtain access to bone from a contiguous focus of infection (e.g. a diabetic foot ulcer) or by haematogenous spread. Osteomyelitis is most commonly caused by Staphylococcus aureus, β-haemolytic streptococci, and—in some situations—aerobic Gram-negative rods. An acute inflammatory response causes oedema within bone and soft tissue, and thrombosis in vessels that can result in bone infarction. Pus may form within cancellous bone and beneath the periosteum, stripping it from the bond and leading to extensive necrosis that sometimes involves an entire bone. The process may become chronic and relapsing....

Chapter.  4891 words.  Illustrated.

Subjects: Rheumatology

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