Chapter

Chronic tubulointerstitial nephritis

Marc E. De Broe, Patrick C. D’Haese and Monique M. Elseviers

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2011 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.210902_update_001

Series: Oxford Textbooks

Chronic tubulointerstitial nephritis

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Chronic tubulointerstitial nephritis is usually asymptomatic, presenting with slowly progressive renal impairment. Urinalysis may be normal or show low-grade proteinuria (<1.5 g/day) and/or pyuria. Diagnosis depends on renal biopsy, which reveals variable cellular infiltration of the interstitium, tubular atrophy, and fibrosis. There are many causes including sarcoidosis, drugs (prescribed and nonprescribed), irradiation, toxins, and metabolic disorders....

Chapter.  12529 words.  Illustrated.

Subjects: Nephrology

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