Haemolytic uraemic syndrome

Paul Warwicker and Timothy H J Goodship

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2011 | e-ISBN: 9780199570973 | DOI:

Series: Oxford Textbooks

Haemolytic uraemic syndrome

Show Summary Details


The haemolytic uraemic syndrome (HUS) is characterized by the triad of: (1) microangiopathic haemolytic anaemia, (2) thrombocytopenia, and (3) acute renal failure. Endothelial cell activation leads to a change in phenotype from an anticoagulant to a procoagulant state.

Diarrhoeal associated (D+) HUS—this accounts for over 90% of cases and is the commonest cause of acute renal failure in children. The usual pathogen is enterohaemorrhagic ...

Chapter.  3534 words. 

Subjects: Nephrology

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.