Chapter

The polycythaemias

Stefan O. Ciurea and Ronald Hoffman

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online May 2010 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.220308

Series: Oxford Textbooks

The polycythaemias

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Polycythaemia or erythrocytosis is characterized by an abnormal increase in the numbers of red blood cells, leading to an elevation in the haemoglobin concentration and haematocrit (>52% in men and >48% in women). The cause may be either (1) primary—due to an intrinsic defect of haemopoietic stem cells; or (2) secondary—due to extrinsic stimulation of progenitor erythroid cells by circulating growth factors; and the condition needs to be distinguished from (3) pseudopolycythaemia—in which haematocrit is raised because the plasma volume is decreased....

Chapter.  9623 words.  Illustrated.

Subjects: Haematology

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