Chapter

Normochromic, normocytic anaemia

D.J. Weatherall

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online November 2011 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.220505_update_001

Series: Oxford Textbooks

Normochromic, normocytic anaemia

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A mild normochromic, normocytic anaemia is a common finding and usually a consequence of other diseases, including (1) anaemia of chronic disorders—associated with chronic infection, all forms of inflammatory diseases, and malignant disease; mechanism unknown but likely to involve multiple factors; typically leads to a reduction in the serum iron concentration with concurrent reduction in the level of transferrin, hence saturation of the iron binding capacity is usually normal or only slightly reduced; (2) other disorders—including renal failure, hypothyroidism, hypopituitarism, marrow failure (aplastic anaemia, infiltration, pure red-cell aplasia), acute blood loss, and polymyalgia rheumatica. Treatment is that of the underlying condition, with a therapeutic trial of corticosteroids justified—after exclusion of underlying blood dyscrasias and paraproteinaemias—in elderly patients with anaemia in association with a very high sedimentation rate....

Chapter.  1791 words. 

Subjects: Haematology

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