Normochromic, normocytic anaemia

D.J. Weatherall

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online November 2011 | e-ISBN: 9780199570973 | DOI:

Series: Oxford Textbooks

Normochromic, normocytic anaemia

Show Summary Details


A mild normochromic, normocytic anaemia is a common finding and usually a consequence of other diseases, including (1) anaemia of chronic disorders—associated with chronic infection, all forms of inflammatory diseases, and malignant disease; mechanism unknown but likely to involve multiple factors; typically leads to a reduction in the serum iron concentration with concurrent reduction in the level of transferrin, hence saturation of the iron binding capacity is usually normal or only slightly reduced; (2) other disorders—including renal failure, hypothyroidism, hypopituitarism, marrow failure (aplastic anaemia, infiltration, pure red-cell aplasia), acute blood loss, and polymyalgia rheumatica. Treatment is that of the underlying condition, with a therapeutic trial of corticosteroids justified—after exclusion of underlying blood dyscrasias and paraproteinaemias—in elderly patients with anaemia in association with a very high sedimentation rate....

Chapter.  1790 words. 

Subjects: Haematology

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.