Chapter

Autoimmune limbic encephalitis and Morvan’s syndrome

Camilla Buckle and Angela Vincent

in Oxford Textbook of Medicine

Published on behalf of Oxford University Press

Published in print May 2010 | ISBN: 9780199204854
Published online November 2012 | e-ISBN: 9780199570973 | DOI: http://dx.doi.org/10.1093/med/9780199204854.003.2422_update_001

Series: Oxford Textbooks

Autoimmune limbic encephalitis and Morvan’s syndrome

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Autoimmune limbic encephalitis—typical presentation is with acute or subacute onset of short term memory loss, seizures and disorientation. MRI characteristically shows striking abnormalities in the hippocampus. Antibodies against cell-surface proteins that are components of voltage-gated potassium channel (VGKC) complexes are found in a high proportion and are probably pathogenic. Aside from supportive care, treatment is with immunosuppression, often comprising corticosteroids with intravenous immunoglobulin and/or plasma exchange....

Chapter.  1394 words.  Illustrated.

Subjects: Neurology

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