Chapter

Pathophysiology

Catherine E. Urch

in Cancer-related Bone Pain

Published on behalf of Oxford University Press

ISBN: 9780199215737
Published online May 2011 | e-ISBN: 9780199606979 | DOI: http://dx.doi.org/10.1093/med/9780199215737.003.0002

Series: Oxford Pain Management Library Opml P

Pathophysiology

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The development of suitable animal models of cancer-induced bone pain (CIBP) has led to an unprecedented increase in our understanding of the pathophysiology of this type of pain. The results of animal studies suggest that CIBP is a unique and complex pain state, with features of both inflammatory and neuropathic pain; they also suggest the possibility of novel therapeutics to treat this type of pain. This chapter will give a brief overview of the current understanding of the pathophysiology of CIBP.

Chapter.  3320 words.  Illustrated.

Subjects: Clinical Oncology ; Pain Medicine

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