Principles of opioid titration

Marie Fallon and Sandra McConnell

in Opioids in Cancer Pain

Published on behalf of Oxford University Press

ISBN: 9780199218806
Published online May 2011 | e-ISBN: 9780199607006 | DOI:

Series: Oxford Pain Management Library OPML P

Principles of opioid titration

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  • Radiation Oncology
  • Pain Medicine


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There is great variation in the dose of opioid required by individual patients. Doses must be tailored to the individual’s need and should start low and then be adjusted (titrated) according to response-up or down. Short acting opioids should be used during the initial titration period and then converted to longer acting formulations when the required dose to achieve pain control is reached. Opioids are useful for neuropathic pain. Adjuvants have an important role in controlling some types of pain where opioids give insufficient analgesia or where adverse effects become intolerable.

Chapter.  1802 words. 

Subjects: Radiation Oncology ; Pain Medicine

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