Marie Fallon and Sandra McConnell

in Opioids in Cancer Pain

Published on behalf of Oxford University Press

Published in print November 2007 | ISBN: 9780199218806
Published online May 2011 | e-ISBN: 9780191739880 | DOI:

Series: Oxford Pain Management Library OPML P


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  • Radiation Oncology
  • Pain Medicine


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Morphine is considered the first line strong opioid for cancer pain and can be administered via different routes. Patients, carers and health care professionals’ concerns regarding morphine must be addressed to allow successful pain management. Morphine is metabolized in the liver and is therefore susceptible to interactions with other drugs. Morphine metabolites are excreted by the kidney and may accumulate in renal impairment. Adverse effects of morphine may be managed by dose reduction, change in route of administration, opioid switching and/or symptomatic measures.

Chapter.  2048 words. 

Subjects: Radiation Oncology ; Pain Medicine

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