Anaesthetic pharmacology and obesity

Mark Bellamy and Michel Struys

in Anaesthesia for the Overweight and Obese Patient

Published on behalf of Oxford University Press

ISBN: 9780199233953
Published online May 2011 | e-ISBN: 9780199607051 | DOI:

Series: Oxford Anaesthesia Library

Anaesthetic pharmacology and obesity

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• Many drugs behave differently in obese and non-obese subjects. • This results from both pharmacokinetic and pharmacodynamic factors. • mg/kg doses provided by manufacturers are based on total body weight in the lean patient population and have limited relevance to total body weight in the obese. • Drug dose may be based on total body weight, ideal body weight, or lean body mass depending on the drug. • There is great variability between individual subjects.

Chapter.  3366 words. 

Subjects: Anaesthetics

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