Adrenocortical cancer

Rossella Libè, Lionel Groussin, Xavier Bertagna and Jérôme Bertherat

in Oxford Textbook of Endocrinology and Diabetes

Second edition

Published on behalf of Oxford University Press

Published in print July 2011 | ISBN: 9780199235292
Published online July 2011 | e-ISBN: 9780199608232 | DOI:

Series: Oxford Textbooks

Adrenocortical cancer

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Adrenocortical cancer (ACC) is among the most aggressive endocrine tumours with an overall very poor prognosis. Morbidity and mortality can be secondary to steroid hormone excess and/or tumour growth and metastases. This potentially poor outcome justifies the importance of considering malignancy in the man-agement of an adrenal mass. The diagnosis of malignancy in a patient with an adrenal tumour relies on careful investigations of clinical, biological, and imaging features before surgery and path-ological examination after tumour removal. Appropriate man-agement and follow-up by an expert multidisciplinary team is important to improve prognosis and to progress in these rare neoplasms.

Chapter.  6753 words.  Illustrated.

Subjects: Endocrinology and Diabetes

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