John A. H. Wass, Peter J. Trainer and Márta Korbonits

in Oxford Textbook of Endocrinology and Diabetes

Second edition

Published on behalf of Oxford University Press

Published in print July 2011 | ISBN: 9780199235292
Published online July 2011 | e-ISBN: 9780199608232 | DOI:

Series: Oxford Textbooks


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Acromegaly is the condition most often associated with an anterior pituitary tumour, which results from growth hormone and insulin-like growth factor 1 (IGF-1) excess. It causes most characteristically enlargement of the hands and feet (Greek: akron, extremities; megas, great). Gigantism, which is the juvenile counterpart of acromegaly, is also caused by a pituitary tumour secreting growth hormone, but it causes excessive growth before epiphyseal fusion. It occurs less frequently than acromegaly because pituitary tumours in children are much less common than in adults.

Chapter.  8800 words.  Illustrated.

Subjects: Endocrinology and Diabetes

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