Chapter

Pituitary carcinoma

John Ayuk, Christopher J. McCabe and Neil J. L. Gittoes

in Oxford Textbook of Endocrinology and Diabetes

Second edition

Published on behalf of Oxford University Press

ISBN: 9780199235292
Published online July 2011 | e-ISBN: 9780199608232 | DOI: http://dx.doi.org/10.1093/med/9780199235292.003.2169

Series: Oxford Textbooks

Pituitary carcinoma

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Most pituitary adenomas are slow-growing, benign tumours. Some do, however, demonstrate aggressive growth characteristics that include infiltration of the dura, bone, and surrounding tissues. Despite such apparent aggressive features, these invasive adenomas are not considered to be truly malignant. To make a diagnosis of pituitary carcinoma requires the presence of a pituitary tumour associated with central nervous system or systemic metastases. Little is known of the pathogenesis of these tumours and the prognostication of future tumour behaviour through clinical, histopathological, or molecular analyses remains challenging (1).

Chapter.  5374 words.  Illustrated.

Subjects: Endocrinology and Diabetes

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