Chapter

Pharmacologic Stress Testing

Ankur Gupta, Gilbert J. Zoghbi and Fadi G. Hage

in Nuclear Cardiac Imaging

Fifth edition

Published on behalf of Oxford University Press

Published in print October 2015 | ISBN: 9780199392094
Published online October 2015 | e-ISBN: 9780199392117 | DOI: http://dx.doi.org/10.1093/med/9780199392094.003.0010
Pharmacologic Stress Testing

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Pharmacological stress testing plays an important role in patient management. Pharmacologic stress agents (adenosine, dipyridamole, regadenoson, dobutamine) produce coronary hyperemia, which is at least as high as that achieved by maximal exercise, by a completely different set of mechanisms than that achieved during exercise. Regadenoson, a relatively newer agent, offers ease of administration and fewer side effects than older stress agents and has become the agent of choice in many stress laboratories. The choice of the stress agent should be individualized based on its indications, contraindications and safety profile. The diagnostic accuracy of pharmacological stress testing for significant coronary artery disease detection is comparable to or exceeds that of exercise myocardial perfusion imaging.

Chapter.  13303 words.  Illustrated.

Subjects: Radiology ; Nuclear Medicine

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