Chapter

Pathophysiology of acute coronary syndromes

Patrick Calvert and Martin Bennett

in Acute Coronary Syndromes

Published on behalf of Oxford University Press

ISBN: 9780199543496
Published online May 2011 | e-ISBN: 9780199607198 | DOI: http://dx.doi.org/10.1093/med/9780199543496.003.0002

Series: Oxford Cardiology Library

Pathophysiology of acute coronary syndromes

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Myocardial infarction is caused by plaque rupture and erosion. Most culprit plaques are less than 70 per cent stenosis. Plaque composition and morphology determine clinical effects rather than plaque size. Systemic therapy, for example via cholesterol reduction, alters plaque composition to a more stable morphology.

Chapter.  1846 words.  Illustrated.

Subjects: Cardiovascular Medicine

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